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Literature summary for 3.2.1.50 extracted from

  • Bandsmer, J.C.; Campbell, T.N.; Cheyne, I.; Choy, F.Y.
    Expression of active alpha-N-acetylglucosaminidase/TAT chimerae in cultured Spodoptera frugiperda cells (2006), Protein Pept. Lett., 13, 353-356.
    View publication on PubMed
Search for more literature for 3.2.1.50

Application

Application Comment Organism
medicine the enzyme is a possible candidate for enzyme replacement therapy, a method for cell entry or transduction has to be found Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression of active alpha-N-acetylglucosaminidase/TAT chimerae in cultured Spodoptera frugiperda cells, establishment of an expression method for optimization of scale-up Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme deficiency causes the Sanfilippo type B syndrome, i.e. the mucopolysaccharidosis type IIIB, an autosomal recessive lysosomal storage disorder, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme deficiency causes the Sanfilippo type B syndrome, i.e. the mucopolysaccharidosis type IIIB, an autosomal recessive lysosomal storage disorder, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
heparan N-sulfatase
-
 Homo sapiens
NAGLU
-
 Homo sapiens